Archive for the ‘Autoimmune Diseases’ Category

Fibromyalgia, Chronic Fatigue, Arthritis, and Other Inflammatory Disorders Helped by Antioxidants and Other Nutritional Supplements

Thursday, July 15th, 2010

With over 15 years experience (both in medical practice and beyond), I have dealt with hundreds of patients, customers, and Associates with chronic inflammatory diseases, which include the Auto-Immunne Diseases (Rheumatoid Arthritis), and quasi-Auto-Immune Dz’s (Dz = Disease), such as Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, etc. Too often, many people have a combination of these diseases.

People suffering with one or a combination of the inflammatory diseases become very discouraged with not finding answers or help, …going doctor-to-doctor and given nothing but steroids and/or anti-depressants.

First off, it is MY belief that the steroids are not the answer. Your immune system is not the problem. The root of the problem is a genetic predisposition of their unique proteins fround throughout that person’s tissues (cells of the muscle, joints, skin, wherever the symptoms arise) to oxidative damage, of which we are all exposed. Oxidative damage will damage someone’s tissues, proteins, celluar structures (enzymes, etc.) more easily than it will another person’s unique molecular structures.

The immune system’s job is to scout around the body looking for foreign or damaged proteins …and it will now see that person’s tissues, proteins, cellular structures as “foreign,” or damaged. In other words, it will not appear to the immune system that these molecular structures are the person’s normal molecules. The immune system doesn’t “recognize” these tissues as its own, so to speak.

Now ..is the problem with the immune system? NO! We have a normal immune system mounting an attack on the abnormal tissues. This leads to inflammation and pain. The immune system cannot get rid of these “foreign” tissues because you keep making them ,…and they keep getting damaged.

Traditionally, the treament has been steroids! Yikes! To do what? To suppress a normal immune system. Does it work? Not long-term, and worse, it doesn’t get to the root of the problem, while at the same time causing damaging side-effects. This just doesn’t make sense to me.

What makes sense is to get to the root of the problem. Obviously, we cannot change one’s genetic structure, but we CAN reduce oxidative damage. We can help protect one’s tissues, proteins, enzymes, cellular structures from free radical attack (the cause of oxidation) … and therefore, there will be LESS damaged, or abnormal molecules than if we did nothing.

So, what’s the antidote to oxidation? Anwer: Anti-Oxidants! Nutritional supplements …can be used safely to reduce oxidative damage, …thereby reducing inflammation and pain. The body will be better maintained. Energy will be created and available better than without nutritional supplements. MOST IMPORTANTLY, the immune system will NOW come around and “see” normal, not damaged, molecules ….molecules that are unique to you, and will now recognize that everything is how it should be ..and will stop the attack.

Without an inflammatory attack, there is less pain, more energy, and healthy tissues.

In my experience, to optimize health in any individuals, …and especially those with MORE OXIDATION .. I give more ANTI-OXIDANTS, all of it safe, and not interfering with medications. (A person should NEVER abruptly stop steroids. Steroids must be weened down slowly, and under the direction of a doctor.)

Personally, I have a specific regimen of nutrtional supplements that I find truly benefits, not only healthy people, but people dealing with more oxidative damage in the form of chronic inflammatory diseases.

Resveratrol, a “Drug” for the Pharmaceutical Companies?

Friday, January 30th, 2009

Last Sunday, CBS’s “60 Minutes” program ran a story about the incredible benefits of the antioxidant RESVERATROL, obtained from the skin of red grapes.  There are numerous medical studies showing the myriad benefits that resveratrol provides.  Like GRAPE SEED EXTRACT, resveratrol helps reduce the risk of heart disease, stroke, hardening of the arteries (atherosclerosis), can benefit those with autoimmune diseases, reduces the risk of age-onset dementia, Alzheimer’s Disease, etc., etc., ….and appears to slow the aging process itself! 

These benefits were extolled in the TV story about resveratrol.  All of it true, and known for at least a decade or more.

Now, this is what REALLY BOTHERED ME:  Not once during this story did they mention the words, “nutritional supplement” or “antioxidant.”  Instead, they kept referring to resveratrol as a “drug.”  As I watched, I couldn’t figure out why they kept saying “the drug,” rather than “the supplement,” or “the antioxidant.”  Then it became crystal clear what was happening.

The researchers in this story (and they are not the only researchers studying resveratrol) had formed a corporation and sold their lab (and souls) to a pharmaceutical company!  Ah-ha!  Furthermore, the sell-out researchers said how they are working on formulating a SYNTHETIC FORM of resveratrol that then can be distributed (sold for massive profit after a patent is obtained) by a pharmaceutical company.  You see, pharmaceutical companies cannot patent a naturally-occurring nutrient, and therefore cannot make huge profits.  That’s why they are always trying to come up with a synthetic form of an effective naturally-occurring substance.  

It’s not about giving people real information so we all can benefit now, it’s obviously about twisting or hiding the information so that they can make an insane profit.  Are they in it for TRUE HEALTH, or solely for the profit?  Certainly there is nothing wrong with making a profit, …the thing that bothers me is holding back what already works very well (and making a reasonable profit off of such sales), and making people believe that our salvation lies with the synthetic formulations that can only be provided from the pharmaceutical industry ….labled as “drugs” so that they can make crushing profits ….at our expense.

This is exactly what happened with the hormone drug Provera.  Decades ago progresterone was discovered from a plant source, and would work just fine in the human body, and would be the identical structure as that found in the human body (known as “bio-identical hormones”).  However, the pharmaceutical company could not make big profits off of the natural form, and therefore tinkered with the molecule until they got it to work (partially), and then could sell it as “Provera.”  However, it does not have all the benefits of progesterone, and there are suggestions that it may increase the risk for heart disease and breast cancer.  But, to the pharmaceutical companies the profit is worth the risk.

Now we have pharmaceutical companies trying to take powerful, effective, safe, and available antioxidant nutrients like resveratrol, and make them into a synthetic form so that they can claim they have a “miracle drug” that provides so many benefits.  On “60 Minutes” the scientists said that the “drug would be ready in about 5 years or so.”

Well, the antioxidant nutrient ALREADY EXISTS!  You can get the benefits of resveratrol (and grape seed extract, and turmeric extract, and others) NOW!  Unfortunately, the pharmacuetical companies know that doctors, the media, and most people only accept such news to as “real” when a pharmaceutical company announces its findings.  Unfortunatley, too few of people realize that there are amazing benefits that they can be enjoying now from many antioxidant nutrients, including resveratrol. 

Don’t be a victim to pharmaceutical company greed.  Don’t wait to obtain the benefits “5 years from now.” Start enjoying the benefits of resveratrol, grape seed extract, turmeric extract now.  (See some of the ”In the News” updates here on my website about turmeric extract, co-enzyme Q10, vitamin D, etc.)

Grape Seed Extract Prevents and Arrests Cancer

Thursday, January 22nd, 2009

In past and recent studies, grape seed extract was shown to stop the growth of human colorectal cancer cells AND cause colorectal cancer cells to undergo apoptosis, …self destruction. Furthermore, recent studies have given further evidence that grape seed extract also inhibits breast cancer, oral cancer, and prostate cancer.  It has been shown to inhibit angiogenesis (growth of blood vessels feeding cancer cells) in breast cancer cells, and most likely works similarly in all types of cancers. Research continues to show evidence that grape seed extract is both safe and effective in the prevention of many types of cancers, induce self-induced destruction (apoptosis) of cancer once present, reduce the risk of arterial plaque formation, maintain heart health, reduce inflammation in all areas of the body (including helping arthritis, fibromyalgia, migraine headaches, asthma and allergies, and provide numerous other health benefits, including crossing the blood-brain barrier and reduce damage and aging of brain cells (which would then may slow or prevent dementia). The extent of the benefits of grape seed extract alone is absolutely astounding.

Since 1995, in my medical practice I recommended grape seed extract (in addition to a broad spectrum multi-antioxidant, chelated mineral formulation, and fish oil) to my patients as a way to boost the immune system, and decrease the risk of heart disease, cancer, type 2 diabetes, inflammatory diseases, multiple sclerosis, autoimmune diseases, and many other medical maladies. The results I personally witnessed was so impressive that I learned to recommend even higher doses of grape seed extract, on the order of 360 to 720 mg per day (for more severe cases).

Recent References (scores more are available): 

Kaur M, Mandair R, Agarwal R, Agarwal C.   Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cells.   Nutr Cancer. 2008;60 Suppl 1:2-11.

Leifert WR, Abeywardena MY.   Grape seed and red wine polyphenol extracts inhibit cellular cholesterol uptake, cell proliferation, and 5-lipoxygenase activity.  Nutr Res. 2008 Dec;28(12):842-50. Epub 2008 Nov 8.

Engelbrecht AM, Mattheyse M, Ellis B, Loos B, Thomas M, Smith R, Peters S, Smith C, Myburgh K.   Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line.   Cancer Lett. 2007 Dec 8;258(1):144-53. Epub 2007 Oct 17.

Lu J, Zhang K, Chen S, Wen W.  Grape seed extract inhibits VEGF expression via reducing HIF-1{alpha} protein expression.  Carcinogenesis. 2009 Jan 8. [Epub ahead of print]

Wen W, Lu J, Zhang K, Chen S.  Grape seed extract inhibits angiogenesis via suppression of the vascular endothelial growth factor receptor signaling pathway.  Cancer Prev Res (Phila Pa). 2008 Dec;1(7):554-61.

Ramchandani AG, Karibasappa GS, Pakhale SS.  Antitumor-promoting effects of polyphenolic extracts from seedless and seeded Indian grapes.  J Environ Pathol Toxicol Oncol. 2008;27(4):321-31.

Huang TT, Shang XJ, Yao GH, Ge JP, Teng WH, Sun Y, Huang YF.  [Grape seed extract inhibits the growth of prostate cancer PC-3 cells]  Zhonghua Nan Ke Xue. 2008 Apr;14(4):331-3.

Chatelain K, Phippen S, McCabe J, Teeters CA, O’Malley S, Kingsley K.  Cranberry and Grape Seed Extracts Inhibit the Proliferative Phenotype of Oral Squamous Cell Carcinomas.  Evid Based Complement Alternat Med. 2008 Jul 23. [Epub ahead of print]