Posts Tagged ‘ladd mcnamara’

Gingko Biloba NOT Associated with Risk of Bleeding

Thursday, May 12th, 2011

For years, doctors have been warning of a possible bleeding side effect of ginko biloba, an flavonoid and terpenoid antioxidant herb that has been found to have many beneficial effects in the body.

Some doctors worried about drug interactions with specific medications, have warned a patient not to use ginko biloba due to an increased risk of bleeding. This warning is normally reserved for NSAIDs, like ibuprofen and aspirin. However, doctors started lumping in gingko biloba with NSAIDs, as causing a potential bleeding interaction.

Although such concerns are very rare, sometimes doctors warn patients about possible side effects of gingko biloba used in combination with anticonvulsive drugs, SSRI antidepressants, and immunosuppressive drugs. However, such concerns are so rare that there may be only one or two case reports …which do not necessarily show a cause and effect of using gingko biloba and the medical concern. For example, Serotonin Syndrome can happen with any SSRI with or without gingko biloba. The fact that a person who experienced Serotonin Syndrome and happen to also be taking gingko biloba does not show a cause and effect. Why blame the gingko biloba, when it was the SSRI could cause this serious problem on its own?

In either case, we can cross the biggest concern that doctors have had about gingko biloba off the list, that of increasing the risk of bleeding.

This month (May 2011), a systematic review and meta-analysis of randomized controlled studies found that there is NOT an associated risk of bleeding with standardized ginko biloba extract. Andrea J Kellermann and Charlotte Kloft (2011). Is There a Risk of Bleeding Associated with Standardized Ginkgo biloba Extract Therapy? A Systematic Review and Meta-analysis. Pharmacotherapy: Volume 31, Issue 5, pp. 490-502. (See reference link below.)

People can continue to use ginko biloba extract for many reasons, and now do so without the worry of abnormal bleeding; nor worry about drug interactions that are normally a concern with aspirin and other NSAIDs.

Eighteen randomized controlled studies involving a total of 1,985 adults were enrolled to receive either ginko biloba exract (GBE) or placebo; 87% were patients with dementia, peripheral artery disease, or diabetes mellitus; 13% were healthy volunteers. Based on meta-analysis of hemostasis outcomes, comparison of mean difference or baseline change between treatment and placebo groups did not indicate a higher bleeding risk associated with standardized GBE. (See reference below.)

In other words, ginko biloba extract does not increase the risk of bleeding problems as do NSAIDs.

Gingko biloba extract is often used alone, or even better, in conjunction with other nutritional supplements such as vitamin E, vitamin C, fish oil, grape seed extract, resveratrol, co-enzyme Q10, olive extract, tumeric extract, and many others, for multiple purposes. A partial list of some of these conditions that antioxidants such as gingko biloba extract and others have been shown to provide benefits are:

Memory
Mood
PMS
Menopause
Macular Degeneration
Glaucoma
Dementia in Alzheimer’s Disease
NON-Alzheimer’s Dementia
Claudication
Mutliple Scelerosis
Tinnitus

Read More: http://pharmacotherapyjournal.org/doi/abs/10.1592/phco.31.5.490

Fibromyalgia, Chronic Fatigue, Arthritis, and Other Inflammatory Disorders Helped by Antioxidants and Other Nutritional Supplements

Thursday, July 15th, 2010

With over 15 years experience (both in medical practice and beyond), I have dealt with hundreds of patients, customers, and Associates with chronic inflammatory diseases, which include the Auto-Immunne Diseases (Rheumatoid Arthritis), and quasi-Auto-Immune Dz’s (Dz = Disease), such as Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, etc. Too often, many people have a combination of these diseases.

People suffering with one or a combination of the inflammatory diseases become very discouraged with not finding answers or help, …going doctor-to-doctor and given nothing but steroids and/or anti-depressants.

First off, it is MY belief that the steroids are not the answer. Your immune system is not the problem. The root of the problem is a genetic predisposition of their unique proteins fround throughout that person’s tissues (cells of the muscle, joints, skin, wherever the symptoms arise) to oxidative damage, of which we are all exposed. Oxidative damage will damage someone’s tissues, proteins, celluar structures (enzymes, etc.) more easily than it will another person’s unique molecular structures.

The immune system’s job is to scout around the body looking for foreign or damaged proteins …and it will now see that person’s tissues, proteins, cellular structures as “foreign,” or damaged. In other words, it will not appear to the immune system that these molecular structures are the person’s normal molecules. The immune system doesn’t “recognize” these tissues as its own, so to speak.

Now ..is the problem with the immune system? NO! We have a normal immune system mounting an attack on the abnormal tissues. This leads to inflammation and pain. The immune system cannot get rid of these “foreign” tissues because you keep making them ,…and they keep getting damaged.

Traditionally, the treament has been steroids! Yikes! To do what? To suppress a normal immune system. Does it work? Not long-term, and worse, it doesn’t get to the root of the problem, while at the same time causing damaging side-effects. This just doesn’t make sense to me.

What makes sense is to get to the root of the problem. Obviously, we cannot change one’s genetic structure, but we CAN reduce oxidative damage. We can help protect one’s tissues, proteins, enzymes, cellular structures from free radical attack (the cause of oxidation) … and therefore, there will be LESS damaged, or abnormal molecules than if we did nothing.

So, what’s the antidote to oxidation? Anwer: Anti-Oxidants! Nutritional supplements …can be used safely to reduce oxidative damage, …thereby reducing inflammation and pain. The body will be better maintained. Energy will be created and available better than without nutritional supplements. MOST IMPORTANTLY, the immune system will NOW come around and “see” normal, not damaged, molecules ….molecules that are unique to you, and will now recognize that everything is how it should be ..and will stop the attack.

Without an inflammatory attack, there is less pain, more energy, and healthy tissues.

In my experience, to optimize health in any individuals, …and especially those with MORE OXIDATION .. I give more ANTI-OXIDANTS, all of it safe, and not interfering with medications. (A person should NEVER abruptly stop steroids. Steroids must be weened down slowly, and under the direction of a doctor.)

Personally, I have a specific regimen of nutrtional supplements that I find truly benefits, not only healthy people, but people dealing with more oxidative damage in the form of chronic inflammatory diseases.

Hints for Swallowing Tablets/Pills for People Who Struggle

Thursday, March 18th, 2010

Here are a few “tricks” you could try for swallowing tablets or pills. As a matter of fact by using the first trick in swallowing tablets, I’m able to swallow as much as 10 tablets at once. However, if it helps anyone be able to swallow just one or two at a time, great.

Trick 1:
After putting the desired number of tablets in your mouth; e.g., 1 to 4 tablets, … take a swig of juice …filling your mouth to the point where your cheeks puff out a little. Then swallow! You’ll find you will more easily swallow tablets with the more liquid in your mouth. It forces your throat open, making swallowing easier. (Although you may do this with water, it seems like juice works better.)

Trick 2:
Keep your head level (or chin slightly down) when swallowing tablets. Tilting your head back “closes off” the esophagus, and opens the trachea …which is how they intubate you when they put you under anesthesia. Of course you’re more likely to choke while trying to swallow that way.

So, put the desired number of tablets in your mouth, then use a flexible straw and suck down juice (or water) with your chin down, …which opens the esophagus, allowing the pills to go down more easily. Again, the more liquid in your mouth when you swallow, the easier the tablets go down.

Getting the Optimal Levels of Vitamin D

Thursday, February 25th, 2010

Measuring Your Vitamin D Status

The only true way to know your vitamin D status, and therefore your proper daily dose, is with a blood test, in which the metabolically-active form of vitamin D, 25-hydroxvitamin D (25-OH-D, or calcidiol) is measured. Relatively recently (over the past 5 to 7 years) when vitamin D’s role in the prevention of degenerative diseases beyond prevention of osteoporosis was recognized, the medical experts recommended a minimum target blood level of 30 ng/ml of 25-hydroxyvitamin D. (I emphasize that “minimum target level” means just that, “minimum!” It does not mean “optimal.”) Therefore, the reference lab ranges was raised to 32 – 100 ng/ml. Most experts in the field of researching and treating vitamin D deficiencies have recommended that “optimal” serum 25-OH-D levels begin at 42 ng/ml, with the ideal target range being achieved between 50 – 80 ng/ml.

What Dose of Vitamin D is Optimal?

The vitamin D dose required to attain a serum level range of 50 – 80 ng/ml will vary from person to person, mostly based upon body mass (weight) and sun exposure. Although this will vary considerably, a 150 lb person who supplements with 2000 IU of vitamin D per day may attain blood level range of 25-OH-D between 30 and 45 ng/ml, depending upon sun exposure. To attain the optimal levels between 50 and 80 ng/ml that same person may need to supplement with 4000 IU per day or more.

On the other hand, a person who weighs 225 lbs. may require 10,000 IU/day to maintain 25-hydroxy vitamin D blood serum levels between 50 and 80 ng/ml. In all instances, the only way to accurately know the “true daily dosage” for a particular person would be to first estimate a starting vitamin D dose, get a serum 25-OH vitamin D test; adjust the dose accordingly, and get re-tested several weeks later.


For more information, read my full article on vitamin D, “D Day: An All-Out Assault on Chronic Disease with Vitamin D” on www.laddmcnamara.com under the “In the News” section.

Vitamins and Minerals Help Maintain a Healthy Blood Pressure

Friday, December 11th, 2009

About 10 days ago, I went to my doctor for a check up, the nurse took my blood pressure; “146/96,” she said. (I thought, “She’s wrong. I’ll just have the doctor re-take it when he gets in here.”) “Hey Phil, your nurse got too high of a reading on me. I don’t have high blood pressure. I think she let the mercury drop too fast, so she didn’t get an accurate reading. I’ve never had high blood pressure.” “Maybe it was because it was the nurse that made your blood pressure rise,” he said with a smile. “Take it again, Phil.” The doctor obliged.

“Ladd, I just got 166/94; you have an auscultatory gap that starts at 166, drops off, and picks back up around 144. The nurse didn’t hear the higher number, but yeah, you got high blood pressure; but, I’m not going to treat it. ”

“You’re darn right, you’re not going to treat it! I DON’T have high blood pressure! I take the BEST Nutritionals in the world, you know that, and I know what they do! Take it again!” I insisted.

“Ladd, you’re upset ….if we take it now, it will be over 200; do you want that? And, if you dropped a few pounds …” “Hey, I just started to drop some pounds …again, and I just started back with my exercise program as well. I take my nutritionals faithfully, I don’t take prescription drugs, AND, I DON’T have high blood pressure! We’re going to talk about something else for a few minutes, and then you’re going to take it again, and then I’ll prove to you that my resting blood pressure is just fine.”

Two minutes later: “128/74 …. Ladd, that’s great. Wow, what a difference! You’re fine!?!” The nurse comes in, “I didn’t think a man of your size and age would ….oh, ..I mean, … well, …yeah, …you’re blood pressure looks great (forced smile), …that’s great.” (I smiled back) Very light-heartedly I said, “Hey, I’ll be back in 3 months, and you’ll see even more evidence on the labs and the scale of just what true health the best nutritionals in the world can provide!”

Here are just a few nutrients that help maintain a healhty blood pressure (along with maintaining a healthy weight, exercise, and a proper diet):

MAGNESIUM:
Extensive research has shown that magnesium is essential to maintain a healthy blood pressure. The National Institutes of Health have recognized magnesium’s critical role in supporting cardiovascular function. Because magnesium is not always plentiful in our foods, and we don’t always eat correctly, supplementation may be the most effective way to maintain a healthy blood pressure. Eur J Public Health. 2004 Sept;14(3):235-9 Circulation. 1989;80(5):1320-7 Drugs Exp Clin Res. 1978;4:49-53

The recommended intake of magnesium to maintain vascular health is 400 to 1000 mg/day (consider at least 400 mg).

alpha Lipoic Acid (ALA) and N-Acetyl-L-Cysteine (NAC):
ALA with magnesium is able to help maintain a healthy blood pressure, even among diabetics. This occurs because these nutrients all increase glutathione levels, which protect bio-mechanisms that regulate arterial tone. ALA with acetyl-L-carnitine help maintain blood pressure. J Clin Hypertens.(Greenwich.). 2007 Apr;9(4):249-55. Hypertension 2002 Feb;39(2):303-307 Eur J Pharmacol 2001 Jul;20;424(2):121-129 Journal of Hypertension 2000, Vol 18, Iss 5, pp 567-573

QUERCETIN:
Studies have demonstrated the ability of the bioflavanoid antioxidant, quercetin to help maintain a healthy blood pressure. High blood pressure is a well-known risk factor for heart attack and stroke.
J Nutr. 2007 Nov;137(11):2405-11 Br J Pharmacol 2001 133:117-24 Curr Opin Clin Nutr Metab Care. 2008 Nov;11(6):733-40

GRAPE SEED EXTRACT:
Polyphenol antioxidants from grape seed extract of at least 180 mg/day (and possibly from other sources, such as the olive extract) also helps to maintain a healthy blood pressure. Siva B, et. al, Effect of polyphenolics extracts of grape seeds (GSE) on blood pressure (BP) in patients with metabolic syndrome (MetS). FASEB. 2006;San Francisco, CA. Clin Sci (Lond). 2004 Nov;107(5):513-7

Co-Enzyme Q10:
Co-Enzyme Q10 provides a myriad of health benefits, including helping to maintain a healthy blood pressure when taken at the level of at least 100 mg/day, …sometimes requiring 200 mg/day. Mol Aspects Med. 1994;15(Suppl):S265-72 J Hum Hypertens. 1999 Mar;13(3):203-8 Mol Aspects Med. 1994;15(Suppl):S257-63

FISH OIL:
Fish Oil, in the dose of 1400 mg of EPA and 1000 mg of DHA/day is associated with maintaining a healthy blood pressure, in addition to a healthy heart. Hypertension. 2006 Feb;47(2):296-308 Circulation. 1993 Aug;88(2):523-33 N Engl J Med. 1989 Apr 20;320(16):1037-43 Clin Exp Pharmacol Physiol. 1991 May;18(5):265-8 Am J Clin Nutr. 1999 Nov;70(5):817-25

Vitamin D:
Vitaimn D deficiency contributes to high blood pressure, diabetes, and inflammation—all of which increase cardiovascular risk. Vitamin D3 in the dose of 1000 to 6000 IU per day (and higher for some people) helps to maintain a healthy blood pressure. Arch Intern Med. 2007 Jun 11;167(11):1159-65 J Nutr. 2005 Nov;135(11):2739S-48S J Steroid Biochem Mol Biol. 2005 Jun;96(1):59-66 J Clin Endocrinol Metab. 2001 Apr;86(4):1633-7 Am J Hypertens. 1995 Sep;8(9):894-901 J Cell Biochem. 2003 Feb 1;88(2):327-31

Vitamin C:
Vitamin C at the dose of at least 1000 mg per day (preferrably higher) may help maintain a healthy blood pressure. J Hypertension, 2000, Vol 18, Iss 4, pp 411-415 Epidemiology. 1992;3:194-202 Lancet. 1999;354(9195):355-64 Circulation. 1998;97:2222-9

Of course, all these nutrients provide multiple health benefits besides helping to maintain a healthy blood pressure!